Product

Ruxolitinib cream 1.5% (Rutinib): what it is used for, how it works, and what it costs

Made by [Manufacturer], Bangladesh · [PLACEHOLDER] g tube · [PLACEHOLDER] per tube · Supplied on prescription to [countries]

Reviewed by Dr [PLACEHOLDER], dermatologist · Last reviewed [PLACEHOLDER date]

Ask on WhatsApp

Is it right for me?

Ruxolitinib cream 1.5% is a non-steroid JAK-inhibitor cream. It is used for two conditions: non-segmental vitiligo and mild to moderate atopic dermatitis (eczema). Your doctor decides; this is to help you prepare the conversation.

Animation to be produced (60–90 seconds): immune T cells attack pigment cells, the interferon-gamma signal passes through JAK1 and JAK2, ruxolitinib blocks it where the cream is applied, and colour can slowly return. A full transcript will sit under the video. Background: Servier Medical Art, CC BY 4.0

What to expect, and when

Eczema: if there is no improvement within 8 weeks, see your doctor again.

Vitiligo: repigmentation is slow. A satisfactory response may take more than 24 weeks of twice-daily use.

How much you will need

Apply a thin layer twice a day. The original product’s label sets upper limits:

Condition	Maximum area	Maximum amount
Eczema, age 12+	20% of body surface	one 60 g tube per week, or one 100 g tube per 2 weeks
Eczema, age 2 to 11	20% of body surface	one 60 g tube per 2 weeks
Vitiligo, age 12+	10% of body surface	one 60 g tube per week, or one 100 g tube per 2 weeks

Do not cover treated skin with dressings. One Rutinib tube holds [PLACEHOLDER] g, so one 60 g tube equals about [PLACEHOLDER] Rutinib tubes.

Generic vs Opzelura

Parameter	Opzelura	Rutinib
Active ingredient and strength	ruxolitinib 15 mg/g, 1.5%	ruxolitinib 1.5%
Manufacturer	Incyte	[Manufacturer]
Regulatory status	FDA: eczema age 2+, vitiligo age 12+; EU: facial vitiligo age 12+	Registered with DGDA, Bangladesh; made under WHO-GMP; not FDA or EMA approved
Pack sizes	60 g, 100 g	[PLACEHOLDER] g
Equivalence data	originator clinical trials	[PLACEHOLDER]

What we don’t know yet [PLACEHOLDER: state honestly whether the manufacturer has published any equivalence data for this cream.] Read the full comparison

Quality and documents

Pack, front and back Batch number and expiry Certificate of analysis, current batch (download PDF) WHO-GMP certificate (download PDF)

Manufacturer [PLACEHOLDER]

DGDA registration no. [PLACEHOLDER]

Current batch [PLACEHOLDER], expiry [PLACEHOLDER]

Storage [PLACEHOLDER]

Safety

Common side effects reported for the original cream include [PLACEHOLDER from label].

Read the full safety page

Price and ordering

Pack	Grams	Price	Price per gram
Rutinib 1.5% cream	[PLACEHOLDER]	[PLACEHOLDER]	[PLACEHOLDER]

Shipping: [PLACEHOLDER] by region. Duties depend on your country.

If customs holds your parcel: [PLACEHOLDER reship or refund policy].

Questions

Do I need a prescription?

Yes. Ruxolitinib cream is a prescription-only medication. A valid medical prescription from a licensed physician is required prior to supply.

Can I use it on my face?

Ruxolitinib cream is authorized for facial application in designated indications such as vitiligo under medical supervision. Avoid direct contact with eyes, mouth, and mucous membranes.

How long does one tube last?

Duration depends directly on the surface area being treated. For localized facial patches, a single tube can last several weeks; larger body surface coverage will exhaust supply faster according to maximum dosing guidelines.

Can children use it?

For atopic dermatitis (eczema), usage is evaluated from age 2 and older. For non-segmental vitiligo, usage is restricted to patients 12 years and older. Always refer to physician assessment.

What if I miss a dose?

Apply the prescribed amount as soon as remembered, unless it is nearly time for your next scheduled dose. Never apply extra cream to compensate for a missed application.

How do I store it?

Store at controlled room temperature, protected from direct heat, sunlight, and moisture. Keep the cap tightly closed and keep out of reach of children. Do not freeze.

Is ruxolitinib cream a steroid?

No. Ruxolitinib is a JAK inhibitor, not a corticosteroid. It blocks JAK1 and JAK2 signalling in the skin. It carries its own warnings; see the safety section above.

What is ruxolitinib cream used for?

The original product, Opzelura, is approved in the US for non-segmental vitiligo from age 12, and for short-term, non-continuous treatment of mild to moderate atopic dermatitis from age 2 in people who are not immunocompromised, when other prescription creams have not worked or are not advisable. Approved uses differ by country [PLACEHOLDER: check local label].

Is there a generic Opzelura?

Rutinib is a generic ruxolitinib 1.5% cream registered in Bangladesh [PLACEHOLDER: DGDA number]. It is not Opzelura and is not approved by the FDA or the EMA. The comparison page sets out what is the same and what is different.